Table 4.
Survival comparison between UTUC-BC and primary BC patients stratified by surgical procedure.
| n | Median Survival (month) | 1-yr OS, % | 3-yr OS, % | 1-yr!!break CSM, % | 3-yr!!break CSM, % | ||
|---|---|---|---|---|---|---|---|
| Non-muscle invasive UTUC-BC | No surgery of primary site | 42 | 68 (45–NA) | 83.2 (72.6–95.4) | 66.9 (53.6–83.6) | 12.0 | 22.9 |
| Local tumor treatment or Partial cystectomy | 521 | 68 (54–84) | 86.6 (83.7–89.6) | 65.6 (61.4–70.1) | 6.1 | 16.2 | |
| Radical cystectomy | 11 | 46 (30–NA) | 81.8 (61.9–100) | 56.1 (30.8–100) | 18.2 | 43.9 | |
| Non-muscle invasive primary BC | No surgery of primary site | 2,946 | 114 (108–118) | 89.8 (89.1–90.4) | 78.0 (77.1–79.0) | 3.0 | 5.8 |
| Local tumor treatment or Partial cystectomy | 142,054 | 121 (120–122) | 93.9 (93.8–94.0) | 82.0 (81.8–82.2) | 1.6 | 4.5 | |
| Radical cystectomy | 712 | 122 (115–140) | 92.9 (91.9–94.0) | 82.0 (80.3–83.8) | 3.6 | 9.4 | |
| Non-muscle invasive primary BC after PSM | No surgery of primary site | 186 | 91 (79–120) | 89.8 (85.5–94.4) | 78.5 (72.5–85.0) | ||
| Local tumor treatment or Partial cystectomy | 2,657 | 115 (103–121) | 92.9 (91.9–93.9) | 80.2 (78.6–81.9) | |||
| Radical cystectomy | 46 | 86 (69–NA) | 91.3 (83.5–99.8) | 74.0 (61.8–88.6) | |||
| Muscle invasive UTUC-BC | No surgery of primary site | 3 | NA | NA | NA | NA | NA |
| Local tumor treatment or Partial cystectomy | 34 | 11 (5–31) | 47.8 (33.3–68.6) | 26.9 (14.9–48.7) | 39.7 | 53.8 | |
| Radical cystectomy | 17 | 20 (14–36) | 76.5 (58.7–99.5) | 13.7 (3.9–48.7) | 11.8 | 62.7 | |
| Muscle invasive primary BC | No surgery of primary site | 765 | 10 (9–11) | 42.2 (38.8–46.0) | 22.0 (19.1–25.3) | 36.1 | 48.6 |
| Local tumor treatment or Partial cystectomy | 18,312 | 19 (18–19) | 61.0 (60.2–61.7) | 34.9 (34.2–35.6) | 25.9 | 41.8 | |
| Radical cystectomy | 12,631 | 52 (49–56) | 79.9 (79.2–80.6) | 56.7 (55.8–57.6) | 13.7 | 30.1 | |
| Muscle invasive primary BC after PSM | No surgery of primary site | 6 | NA | NA | NA | ||
| Local tumor treatment or Partial cystectomy | 160 | 22 (17–39) | 65.0 (57.9–72.9) | 41.5 (34.2–50.4) | |||
| Radical cystectomy | 99 | 49 (36–77) | 81.4 (74.0–89.5) | 56.9 (47.4–68.3) |
UTUC-BC, bladder recurrence after radical nephroureterectomy of upper urinary tract urothelial carcinoma; BC, bladder cancer; OS, overall survival; CSM, cancer-specific mortality; NA, not available; PSM, propensity score matching.