Table 1.
# | gender | age | co-morbidities | COVID symptoms | COVID category | COVID treatment | CML dg. calendar year and prognostic score | TKI | Molecular remission status at COVID | COVID outcome |
---|---|---|---|---|---|---|---|---|---|---|
1 | F | 88 | hypertension, generalized arteriosclerosis | weakness | mild | none | 2013 Sokal score 1,01 (intermediate) ELTS score 2,638 (high risk). | imatinib | MR5 | recovered |
2 | M | 43 | none | weakness, sore throat, fever | mild | amoxicillin + clavulanic acid | 2006 Sokal score 0,64 (low) ELTS 2,0525 (intermediate risk). | imatinib | MR4 | recovered |
3 | M | 47 | NSTEMI subtotal CX occlusion, PCI in 2015 | coughing, fever, diarrhoe, anosmia | mild | azithromycin | 2010 Sokal score (0,66 low risk) ELTS 3,9847 (high risk). | bosutinib (fourth line) | MR4 | recovered |
COVID-19 IgG antibodies (using an Abbott SARS-CoV-2-Ig test) were found to be present in our patients 6 month, 10 weeks and 5 weeks following the COVID-19 infection, respectively. As vitamin D has been suggested to be an additional factor in improving outcomes in patients with COVID 19 infections, we also tested for 25-OH vitamin D serum levels at these time points. Serum 25-OH vitamin D levels were found to be normal in all the three patients (44.6 ng/ml, 33.5 ng/ml and 48.1 ng/ml, respectively (normal values: 30–60 ng/ml)).
NSTEMI: non-ST-elevation myocardial infarction. PCI: percutaneous coronary intervention. CX: circumflex artery. ELTS: EUTOS (EUropean Treatment Outcome Study) long-term survival score.