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. 2021 Mar 1;13(1):e2021022. doi: 10.4084/MJHID.2021.022

Table 1.

Main clinical characteristics, treatment and disease course of three patients with CML and COVID-19 infection.

# gender age co-morbidities COVID symptoms COVID category COVID treatment CML dg. calendar year and prognostic score TKI Molecular remission status at COVID COVID outcome
1 F 88 hypertension, generalized arteriosclerosis weakness mild none 2013 Sokal score 1,01 (intermediate) ELTS score 2,638 (high risk). imatinib MR5 recovered
2 M 43 none weakness, sore throat, fever mild amoxicillin + clavulanic acid 2006 Sokal score 0,64 (low) ELTS 2,0525 (intermediate risk). imatinib MR4 recovered
3 M 47 NSTEMI subtotal CX occlusion, PCI in 2015 coughing, fever, diarrhoe, anosmia mild azithromycin 2010 Sokal score (0,66 low risk) ELTS 3,9847 (high risk). bosutinib (fourth line) MR4 recovered
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COVID-19 IgG antibodies (using an Abbott SARS-CoV-2-Ig test) were found to be present in our patients 6 month, 10 weeks and 5 weeks following the COVID-19 infection, respectively. As vitamin D has been suggested to be an additional factor in improving outcomes in patients with COVID 19 infections, we also tested for 25-OH vitamin D serum levels at these time points. Serum 25-OH vitamin D levels were found to be normal in all the three patients (44.6 ng/ml, 33.5 ng/ml and 48.1 ng/ml, respectively (normal values: 30–60 ng/ml)).

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NSTEMI: non-ST-elevation myocardial infarction. PCI: percutaneous coronary intervention. CX: circumflex artery. ELTS: EUTOS (EUropean Treatment Outcome Study) long-term survival score.