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. Author manuscript; available in PMC: 2022 Jan 1.
Published in final edited form as: JCSM Rapid Commun. 2020 Aug 7;4(1):3–15. doi: 10.1002/rco2.18

Figure 4.

Figure 4.

Cancer-induced cardiac atrophy disrupts mt-mRNA translation products but not mt-mRNA translation machinery. (A) Mitochondrial transcription and translation machinery (TFAM, mtIF2, mtIF3, TACO1) and a mt-mRNA translation product (Cytb) normalized to total protein content by PonceauS and (B) normalized to mitochondrial content marker VDAC in PBS and LLC hearts. (C) Immunoblot analysis of OXPHOS complex content as determined through protein subunits required for complex formation. Specific target for each subunit is indicated in the materials and methods section. (D) Sample immunoblot images of protein target indicated. Bands were cropped at indicated molecular weight and to show each group side-by-side. * indicates p < 0.05.