Table 1.
Summary of sociodemographic and clinical characteristics at genotyping by sub-region
| Demographic/clinical variable | Centre-South | Centre-North | North-West | North-East | West | East | South-West | South-East |
|---|---|---|---|---|---|---|---|---|
| Number of individuals | 294 | 190 | 269 | 239 | 280 | 244 | 236 | 254 |
| Median age, years (IQR) | 28 (24–35) | 31 (25–39)* | 32 (26–40)**** | 29 (24–36) | 31 (26–40)*** | 30 (24–39) | 30 (24–37) | 27 (24–36) |
| Proportion of females, n (%) | 24 (8.2) | 27 (14.2)* | 58 (21.6)**** | 38 (15.9)** | 42 (15.0)* | 47 (19.3)*** | 51 (21.6)**** | 41 (16.1)** |
| Median viral load, log copies/mL (IQR) | 5.0 (4.4–5.4) | 4.9 (4.4–5.4) | 4.7 (4.1–5.4)* | 4.8 (4.2–5.4) | 5.0 (4.4–5.5) | 5.0 (4.4–5.6) | 4.8 (4.3–5.4) | 4.9 (4.4–5.4) |
| Median CD4+ T counts, cells/mm3 (IQR) | 258 (104–406) | 257 (63–467) | 268 (96–470) | 241 (97–456) | 212 (66–412) | 176 (59–330)** | 210 (91–345) | 235 (87–420) |
| Median % CD4+ T counts, % (IQR) | 13 (7–20) | 15 (7.7–22) | 17 (8.5–26)*** | 14 (8–24) | 15 (7–22) | 12 (5–18) | 13 (7.2–19) | 14 (7–19) |
| Prior antiretroviral exposure, n (%) | 9 (3.1) | 12 (6.3) | 30 (11.2)*** | 12 (5.0) | 26 (9.3)** | 23 (9.4)** | 32 (13.6)**** | 14 (5.5) |
| Marital status, n (%) | ||||||||
| Single | 245 (83.3) | 145 (76.3) | 179 (66.5)**** | 173 (72.4)** | 213 (76.1)* | 161 (66.0)**** | 168 (71.2)** | 187 (73.6)** |
| Married | 11 (3.7) | 14 (7.4) | 26 (9.7)** | 11 (4.6) | 25 (8.9)* | 15 (6.1) | 23 (9.7)** | 25 (9.8)** |
| domestic partnership | 31 (10.5) | 23 (12.1) | 34 (12.6) | 52 (21.8)*** | 36 (12.9) | 46 (18.9)** | 40 (16.9)* | 38 (15.0) |
| unknown | 7 (2.4) | 8 (4.2) | 30 (11.2)**** | 3 (1.3) | 6 (2.1) | 22 (9.0)*** | 5 (2.1) | 4 (1.6) |
| Education, n (%) | ||||||||
| elementary | 19 (6.5) | 25 (13.2)* | 38 (14.1)** | 28 (11.7)* | 51 (18.2)**** | 49 (20.1)**** | 58 (24.6)**** | 36 (14.2)** |
| high school | 139 (47.3) | 91 (47.9) | 137 (50.9) | 132 (55.2) | 123 (43.9) | 122 (50.0) | 104 (44.1) | 153 (60.2)** |
| degree/technician | 128 (43.5) | 57 (30.0)** | 57 (21.2)**** | 72 (30.1)** | 90 (32.1)** | 48 (19.7)**** | 63 (26.7)**** | 57 (22.4)**** |
| postgraduate | 5 (1.7) | 8 (4.2)* | 3 (1.1)** | 2 (0.8)** | 6 (2.1)* | 1 (0.4) | 1 (0.4)*** | 0 (0.0)** |
| none | 0 (0.0) | 4 (2.1)* | 4 (1.5) | 4 (1.7)* | 3 (1.1) | 7 (2.9)** | 8 (3.4)** | 2 (0.8) |
| unknown | 3 (1.0) | 5 (2.6) | 30 (11.2)**** | 1 (0.4) | 7 (2.5) | 17 (7.0)*** | 2 (0.8) | 6 (2.4) |
| Employment, n (%) | ||||||||
| employed | 163 (55.4) | 102 (53.7) | 104 (38.7)**** | 130 (54.4) | 147 (52.5) | 104 (42.6)** | 126 (53.4) | 122 (48.0) |
| unemployed | 78 (26.5) | 65 (34.5) | 109 (40.5)*** | 91 (38.1)** | 98 (35.0)* | 82 (33.6) | 89 (37.7)** | 105 (41.3)*** |
| student | 45 (15.3) | 16 (8.4) | 19 (7.1) | 16 (6.7) | 26 (9.3) | 34 (13.9) | 14 (5.9) | 20 (7.9) |
| unknown | 8 (2.7) | 7 (3.7) | 37 (13.8)**** | 2 (0.8) | 9 (3.2) | 24 (9.8)*** | 7 (3.0) | 7 (2.8) |
| HIV transmission risk factor, n (%) | ||||||||
| heterosexual | 63 (21.4) | 59 (31.1)* | 86 (32.0)** | 62 (25.9) | 92 (32.9)** | 88 (36.1)*** | 108 (45.8)**** | 85 (33.5)** |
| MSM | 157 (53.4) | 113 (59.5) | 111 (41.3)** | 129 (54.0) | 146 (52.1) | 115 (47.1) | 110 (46.6) | 138 (54.3) |
| bisexual | 10 (3.4) | 8 (4.2) | 8 (3.0) | 27 (11.3)*** | 21 (7.5)* | 17 (7.0) | 13 (5.5) | 13 (5.1) |
| PWID | 5 (1.7) | 4 (2.1) | 23 (8.6)*** | 4 (1.7) | 10 (3.6) | 2 (0.8) | 0 (0.0) | 5 (2.0) |
| unknown | 59 (20.1) | 6 (3.2)**** | 41 (15.2) | 17 (7.1)**** | 11 (3.9)**** | 22 (9.0)*** | 5 (2.1)**** | 13 (5.1)**** |
| Clinical symptoms, n (%) | ||||||||
| asymptomatic | 138 (46.9) | 63 (33.2)** | 42 (15.6)**** | 96 (40.2) | 110 (39.3) | 88 (36.1)* | 96 (40.7) | 77 (30.3)**** |
| symptomatic non-AIDS | 37 (12.6) | 19 (10.0) | 14 (5.2)** | 45 (18.8) | 33 (11.8) | 32 (13.1) | 36 (15.3) | 14 (5.5)** |
| symptomatic AIDS | 49 (16.7) | 105 (55.3)**** | 171 (63.6)**** | 75 (31.4)**** | 119 (42.5)**** | 78 (32.0)**** | 78 (33.1)**** | 141 (55.5)**** |
| unknown | 70 (23.8) | 3 (1.6)**** | 42 (15.6)* | 23 (9.6)**** | 18 (6.4)**** | 46 (18.9) | 26 (11.0)*** | 22 (8.7)**** |
| Subtype, n (%) | ||||||||
| B | 292 (99.3) | 185 (97.4) | 269 (100.0) | 238 (99.6) | 274 (97.9) | 242 (99.2) | 232 (98.3) | 251 (98.8) |
| non-B | 2 (0.7) | 5 (2.6) | 0 (0.0) | 1 (0.4) | 6 (2.1) | 2 (0.8) | 4 (1.7) | 3 (1.2) |
Centre-South was used as a reference for comparisons.
*
P < 0.05,
**
P < 0.01,
***
P < 0.001,
****
P < 0.0001 by Fisher exact or Mann–Whitney test. PWID, people who inject drugs.