Fig. 3.

Risk of death and interaction between clusters, age and dexmedetomidine treatment. CrI credible interval. The effect estimates, odds ratio (OR) for the interaction between dexmedetomidine allocation, cluster assignment and six different cut-offs of age categories are presented. OR < 1.0 represents a favorable outcome and > 1.0 represents unfavorable outcome with the use of dexmedetomidine. a Odd ratios according to cluster, operative cluster 1 depicts a high probability of benefit with increased age. b Probability of benefit with the allocation to dexmedetomidine was higher in cluster 1 but mainly in those > 50 years old. c Probability of > 10% benefit with the allocation to dexmedetomidine was higher in cluster 1 but mainly in those > 60 years. d Probability of > 10% harm with the allocation to dexmedetomidine was higher in cluster 2, non-operative, mainly in patients younger than 50 years