Table 1.
Univariate analysis of risk factors predicting surgical site infection following mesh repair of groin hernia.
| Variables | All | SSI | No SSI | OR | 95%CI | P-value |
| Total | 1177 | 39 (3.2)∗ | 1138 (96.8)∗ | |||
| Demographic factors | ||||||
| Age (yr) | 59 (42–70) | 61 (41–70) | 63 (51–71) | 0.988 | 0.969–1.006 | .192 |
| Gender (male) | 1124 (95.5) | 39 (100) | 1085 (92.2) | 1.856 | 0.250–13.779 | .545 |
| BMI (kg/m2) | 22.8 (20.6–24.6) | 23.8 (21.3–25.3) | 22.7 (20.5–24.5) | 1.114 | 1.008–1.231 | .034 |
| Current smoker, yes | 139 (11.8) | 10 (25.6) | 129 (11.3) | 2.697 | 1.285–5.663 | .009 |
| Comorbidity | ||||||
| Diabetes mellitus, yes | 57 (4.8) | 5 (12.8) | 52 (4.6) | 3.071 | 1.154–8.176 | .025 |
| Hypertension, yes | 199 (16.9) | 7 (17.9) | 192 (16.9) | 1.078 | 0.469–2.478 | .860 |
| Pulmonary disease, yes | 56 (4.8) | 2 (5.1) | 54 (4.7) | 1.085 | 0.255–4.621 | .912 |
| Malignancy, yes | 44 (3.7) | 3 (7.7) | 41 (3.6) | 2.230 | 0.659–7.540 | .197 |
| Chronic drug treatment | ||||||
| Steroid, yes | 55 (4.7) | 2 (5.1) | 53 (4.7) | 1.107 | 0.260–4.714 | .891 |
| Statin, yes | 53 (4.5) | 1 (2.6) | 52 (4.6) | 0.550 | 0.074–4.081 | .558 |
| Procedure factors | ||||||
| ASA score (III–IV), yes | 65 (5.5) | 3 (7.7) | 62 (5.5) | 1.446 | 0.433–4.827 | .549 |
| Type of hernia | 0.610 | 0.263–1.419 | .251 | |||
| Direct | 173 (14.7) | 5 (12.8) | 168 (14.8) | |||
| Indirect | 962 (81.7) | 34 (87.2) | 928 (81.5) | |||
| Combined | 42 (3.6) | 0 | 42 (3.7) | |||
| Hernia characteristics | 0.844 | 0.519–1.372 | .493 | |||
| Left | 412 (35.0) | 15 (38.5) | 397 (34.9) | |||
| Right | 600 (51.0) | 20 (51.3) | 580 (51.0) | |||
| Bilateral | 165 (14.0) | 4 (10.3) | 161 (14.1) | |||
| Duration of inguinal hernia presentation (years) | 1.0 (0.2–3.1) | 2.0 (0.5–3.6) | 1.0 (0.2–3.1) | 1.006 | 0.998–1.014 | .139 |
| Repair of recurrence, yes | 29 (2.5) | 3 (7.7) | 26 (2.3) | 0.281 | 0.081–0.970 | .045 |
| Preoperative stay (days) | 2.0 (2.0–3.0) | 2.0 (2.0–3.0) | 2.0 (2.0–3.0) | 0.984 | 0.820–1.182 | .865 |
| Pre-operative blood results† | ||||||
| WBC (×109/L) | 6.8 (5.7–8.1) | 6.8 (5.9–8.5) | 6.8 (5.7–8.1) | 1.014 | 0.953–1.078 | .667 |
| NEU (×109/L) | 3.9 (3.1–2.0) | 6.6 (6.0–7.8) | 3.8 (3.1–4.8) | 1.505 | 1.350–1.678 | .000 |
| LYM (×109/L) | 2.0 (1.6–2.5) | 1.7 (1.2–2.2) | 2.0 (1.6–2.5) | 0.477 | 0.295–0.771 | .003 |
| MON (×109/L) | 0.5 (0.4–0.6) | 0.6 (0.5–0.7) | 0.5 (0.4–0.6) | 1.305 | 0.554–3.072 | .542 |
| EOS (×109/L) | 0.2 (0.1–0.3) | 0.1 (0.1–0.3) | 0.2 (0.1–0.3) | 1.887 | 0.761–4.679 | .170 |
| BASO (×109/L) | 0.03 (0.02–0.04) | 0.03 (0.02–0.04) | 0.03 (0.02–0.04) | 3.472 | 0.108–111.265 | .482 |
| HGB (g/L) | 141.0 (130.0–150.0) | 138.0 (127.0–144.0) | 141.0 (130.0–150.0) | 0.988 | 0.972–1.003 | .988 |
| PLT (×109/L) | 217 (184–253) | 249 (212–299) | 215 (183–253) | 1.008 | 1.004–1.013 | .000 |
| ALB (g/L) | 40.5 (37.6–42.8) | 38.8 (36.4–42.5) | 40.6 (37.7–42.9) | 0.924 | 0.866–0.986 | .018 |
| NLR | 2.0 (1.4–2.7) | 4.0 (3.0–6.7) | 1.9 (1.4–2.6) | 1.037 | 1.004–1.071 | .029 |
| PLR | 107.0 (85.2–143.5) | 142.6 (115.8–212.8) | 105.9 (83.5–142.1) | 1.002 | 1.000–1.003 | .045 |
| LMR | 3.8 (2.9–5.0) | 3.2 (1.9–4.2) | 3.9 (3.0–5.0) | 1.011 | 0.998–1.024 | .108 |
| Intraoperative factors | ||||||
| Surgical technique | 5.824 | 2.261–14.998 | .001 | |||
| Laparoscopic | 530 (45.0) | 5 (12.8) | 525 (46.1) | |||
| Open | 647 (55.0) | 34 (87.2) | 613 (53.9) | |||
| Duration of surgery (min) | 73 (53–93) | 76 (61–96) | 72 (53–93) | 1.006 | 0.998–1.014 | .139 |
| Intraoperative blood loss (ml) | 5 (5–10) | 5 (5–10) | 5 (5–10) | 1.033 | 0.991–1.077 | .123 |
| Use of postsurgical drains, yes | 278 (23.6) | 7 (17.9) | 271 (23.8) | 0.700 | 0.305–1.604 | .399 |