Table 5. CD4 T cell count recovery rates within 3 year of antiretroviral therapy according to baseline characteristics (an increase of >50 cells/μL).
Baseline characteristics* | Recovery | Total | Statistics | ||
---|---|---|---|---|---|
Non-responder | Recovered | ||||
Clinical stage | Stage IV | 10 | 28 | 38 | Recovery (stage IV) = 73.7%; p < 0.001 |
Stage I—III | 10 | 118 | 128 | Recovery (stage I-III) = 92.2%; p < 0.001 | |
Total | 20 | 146 | 166 | HR = 1.4 (0.9–2.1)†; p > 0.05 | |
CD4 T cell count (cell/μL) | < 200 | 10 | 31 | 41 | Recovery (<200) = 75.6%; p < 0.01 |
≥200 | 10 | 115 | 125 | Recovery (≥200) = 87.9%; p < 0.01 | |
Total | 20 | 146 | 166 | HR = 1.37 (0.9–2.0)†; p >0.05 | |
TB after initiation of ART‡ | Yes | 7 | 13 | 20 | Recovery (TB) = 65%; p < 0.01 |
No | 13 | 124 | 137 | Recovery (no TB) = 91.2%; p < 0.01 | |
Total | 20 | 137 | 157 | HR = 1.7 (1.0–3.0) †; p <0.05 |
abbreviations: TB, tuberculosis; OR, odds ratio; HR, hazard ratio
*-only characteristics demonstrated significant difference in recovery rate are presented in the table (Fisher’s exact test, p < 0.05)
†-95% confidential interval for hazard ratio (Wald test)
‡-9 patients with TB detected before ART were excluded from analysis