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. 2021 Jan 13;295(52):18023–18035. doi: 10.1074/jbc.RA120.015661

Table 1.

Properties of different human and murine Mx proteins

Protein Cellular localization Illustrative antiviral activitya References
Human MxA Cytoplasmic condensates with some tethered to intermediate filaments Versus both FLUAV and VSV 9, 29,30, 31, 32, 33, 34,35
Human MxB (full-length) Cytoplasmic face of nuclear pores Versus HIV; not versus FLUAV nor VSV 31, 39,40, 41, 42, 43,44
Cytoplasmic condensates Our inference
Murine Mx1 Nuclear condensates Versus FLUAV; not VSV This study and Refs. 2931, 35, 36
Cytoplasmic intermediate filaments and condensates Versus VSV This study
Murine Mx2 Cytoplasmic structures Versus VSV; not FLUAV 31, 3537

a

See Refs. 31, 35, and 44 for detailed antiviral spectrum reported in the previous literature.