Table 4.
Interaction partners of CK1δ. In case interaction was confirmed by co-immunoprecipitation, yeast two-hybrid screen, or similar approaches reported interaction partners for CK1δ are listed in the following table. Furthermore, information is provided if the respective protein is target for CK1δ-mediated phosphorylation (●: yes, -: no). In case the respective protein is only phosphorylated by isoforms other than CK1δ or only single family members of the indicated interaction partners are target for CK1δ-mediated phosphorylation this information is provided in parentheses.
| Protein | Phosphorylation by CK1(S) | References |
|---|---|---|
| 14-3-3 ζ | - (● CK1α) | (Dubois et al., 1997, Zemlickova et al., 2004) |
| AKAP450 (A-kinase anchor protein 450) | - | (Sillibourne et al., 2002) |
| Atoh1 (atonal bHLH transcription F factor1) | ● | (Cheng et al., 2016) |
| Axin 1 and 2 | ● | (Amit et al., 2002, Gao et al., 2002) |
| Chk1 (checkpoint kinase 1) | - | (Bischof et al., 2013) |
| CK1BP (casein kinase-1 binding protein) | ● | (Yin et al., 2006) |
| CPI-17 (protein kinase C-potentiated myosin phosphatase inhibitor of 17 kDa) | - | (Zemlickova et al., 2004) |
| DDX3X (DEAD-box RNA helicase 3 X-linked) | - (● CK1ε) | (Cruciat et al., 2013, Dolde et al., 2018) |
| Dvl1 (dishevelled 1) | ● | (Gao et al., 2002) |
| EB1 (microtubule plus-end-binding protein1) | ● | (Zyss et al., 2011) |
| FAM83A, B, E, and H | ● (FAM83H) | (Kuga et al., 2016, Wang et al., 2016, Fulcher et al., 2018) |
| LEF-1 (lymphocyte enhancer factor-1) | ● | (Hammerlein et al., 2005) |
| MAP1A (microtubule-associated protein 1A) | ● | (Wolff et al., 2005) |
| NFAT1, 2, and 4 (nuclear factor of activated T cells) | ● (NFAT1) | (Okamura et al., 2004) |
| p53 (tumor protein 53) | ● | (Milne et al., 1992, Venerando et al., 2010) |
| PER1 and 2 (period circadian protein homolog 1 and 2) | ● | (Vielhaber et al., 2000, Lee et al., 2001, Miyazaki et al., 2004, Etchegaray et al., 2009, Shanware et al., 2011) |
| RanBPM (Ran-binding protein in the MTOC) | ● | (Wolff et al., 2015) |
| Snapin (SNARE-associated protein snapin) | ● | (Wolff et al., 2006) |
| SPRY2 (sprouty2) | ● | (Yim et al., 2014) |
| Tau (MAPT, microtubule-associated protein tau) | ● | (Behrend et al., 2000b, Li et al., 2004, Kawakami et al., 2008) |