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. 2021 Mar 5;10(1):396–399. doi: 10.1080/22221751.2021.1889932

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© 2021 The Author(s). Published by Informa UK Limited, trading as Taylor & Francis Group, on behalf of Shanghai Shangyixun Cultural Communication Co., Ltd

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Figure 1. — Clinical data of the lung transplantation recipient and genetic features of the two plasmids (pNDM22937 and pVir22937) of K. pneumoniae strain KP22937. (A) Time and site of isolation of K. pneumoniae from the patient and antimicrobial therapy. TZP, piperacillin/tazobactam; VA, vancomycin; CBF, caspofungin; AMB, amphotericin B; TGC, tigecycline; MEM, meropenem; ATM, aztreonam; VRC, voriconazole; PLB, polymyxin B. (B) Circular plasmid maps of the two plasmids (red colour) and their respective reference plasmids (blue and orange colours). Purple colour region is the genomic island in the plasmid pNDM22937. Red text on the plasmid maps indicates the main virulence determinants and resistance gene of strain KP22937. (C) Genetic contents of bla_NDM-5 gene. ORFs are indicated by arrows. Sequences of shared homology between two plasmids are marked by grey shading.