Table 1. Baseline demographic and clinical characteristics of each group.
| Group 1 | Group 2 | Total | p-value | |
|---|---|---|---|---|
| Age | 50.38 (±11.90) | 67.40 (±14.32) | 57.33 (±15.34) | ***< 0.001b |
| Sex (male:female) | M:12, F:17 (F: 58.6%) | M:9, F:11 (F: 55.0%) | M:21, F:28 (F: 57.1%) | 0.801c |
| Meibography score | 3.24 (±0.79) | 5.15 (±0.37) | 4.02 (±1.15) | ***< 0.001b |
| OSDI | 47.55 (±23.05) | 31.95 (±17.94) | 41.18 (±22.30) | *0.014a |
| TBUT (seconds) | 5.87 (±1.75) | 5.88 (±1.32) | 5.87 (±1.57) | 0.977a |
| Schirmer’s test (mm) | 7.26 (±4.34) | 6.78 (±4.76) | 7.06 (±4.48) | 0.521b |
| Expressibility of meibum | 22.28 (±11.10) | 19.80 (±11.99) | 21.27 (±11.42) | 0.461a |
| Cornea staining score | 1.34 (±0.54) | 1.38 (±0.83) | 1.36 (±0.66) | 0.966b |
| Meibum quality score | 2.12 (±0.42) | 2.32 (±0.73) | 2.20 (±0.57) | 0.063b |
Data are presented as number and mean value±standard deviation. Group 1: mild to moderate dropout of the meibomian gland; Group 2: severe dropout of the meibomian gland.
a: Independent samples t-test results.
b: Mann-Whitney U test results.
c: chi-squared (χ2) test result. OSDI: ocular surface disease index; TBUT: tear film break-up time.
* p<0.05,
*** p<0.001.