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. 2021 Mar 8;16(3):e0247365. doi: 10.1371/journal.pone.0247365

Table 2. Clinical signs and symptoms before and after hyperthermic and mechanical squeezing treatments in MGD patients with mild to moderate dropout of the meibomian gland (Group 1).

Before treatment After treatment p-value
Meibography score 3.24 (±0.79) 2.76 (±1.02) **0.005b
OSDI 47.55 (±23.05) 31.21 (±15.33) ***< 0.001a
TBUT (seconds) 5.87 (±1.75) 7.80 (±2.49) ***< 0.001b
Schirmer’s test (mm) 7.26 (±4.34) 7.31 (±3.58) 0.909b
Expressibility of meibum 22.28 (±11.10) 33.33 (±11.84) ***< 0.001a
Cornea staining score 1.34 (±0.54) 1.03 (±0.72) *0.039b
Meibum quality score 2.12 (±0.42) 2.07 (±0.37) 0.435b

Data are presented as number and mean value ±standard deviation.

a: Paired t-test results.

b: Wilcoxon signed rank test results. OSDI: ocular surface disease index; TBUT: tear film break-up time.

* p<0.05,

** p<0.01,

*** p<0.001.