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. 2021 Mar 8;16(3):e0247365. doi: 10.1371/journal.pone.0247365

Table 3. Clinical signs and symptoms before and after hyperthermic and mechanical squeezing treatments in MGD patients with severe dropout of the meibomian gland (Group 2).

Before treatment After treatment p-value
Meibography score 5.15 (±0.37) 4.75 (±0.64) *0.021b
OSDI 31.95 (±17.94) 23.65 (±16.22) *0.049a
TBUT (seconds) 5.88 (±1.32) 9.03 (±3.04) ***< 0.001b
Schirmer’s test (mm) 6.78 (±4.76) 5.58 (±1.73) 0.226b
Expressibility of meibum 19.80 (±11.99) 29.83 (±11.92) **0.001a
Cornea staining score 1.38 (±0.83) 1.15 (±0.56) 0.319b
Meibum quality score 2.33 (±0.73) 2.25 (±0.55) 0.492b

Data are presented as number and mean value ±standard deviation.

a: Paired t-test results.

b: Wilcoxon signed rank test results. OSDI: ocular surface disease index; TBUT: tear film break-up time.

* p<0.05,

** p<0.01,

*** p<0.001.