Table 4. Comparison of changes in clinical signs and symptoms between the two groups.
| Group 1 | Group 2 | p-value | |
|---|---|---|---|
| Meibography score | ***0.48 (±0.78) | *0.40 (±0.68) | 0.864b |
| OSDI | **16.34 (±17.42) | *8.30 (±17.66) | 0.121a |
| TBUT (seconds) | ***-1.93 (±2.46) | ***-3.15 (±3.16) | 0.416b |
| Schirmer’s test (mm) | -0.05 (±5.45) | 1.20 (±3.91) | 0.528b |
| Expressibility of meibum | ***-11.12 (±13.58) | **-10.03 (±12.02) | 0.773a |
| Cornea staining score | *0.31 (±0.85) | 0.23 (±0.85) | 0.731a |
| Meibum quality score | 0.05 (±0.41) | 0.08 (±0.61) | 0.450b |
Data are presented as number and mean value ±standard deviation.
a: Independent samples t-test results.
b: Mann-Whitney U test results. OSDI: ocular surface disease index; TBUT: tear film break-up time. Asterisks indicate values with significant differences before and after treatment in each group (
* p<0.05,
** p<0.01,
*** p<0.001).