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. Author manuscript; available in PMC: 2022 Mar 15.
Published in final edited form as: Brain Res. 2021 Jan 7;1755:147263. doi: 10.1016/j.brainres.2020.147263

Figure 1:

Figure 1:

CLBP is associated with greater brain age over chronological age - Association between chronological age and predicted brain age in healthy controls (HC, blue) and those with CLBP (red) are shown. Trendlines and 95% confidence intervals (shaded areas) are plotted as well. The CLBP group showed a significantly steeper trend of brain age increases over chronological age representative of a discrepancy in aging exacerbated over the lifespan.