Table 1.
Clinical characteristics of the 83 participators ().
| Clinical characteristics | Control group (n = 20) | S0 group (n = 10) | S1 group (n = 15) | S2 group (n = 13) | S3 group (n = 10) | S4 group (n = 10) | CC group (n = 13) | DC group (n = 12) |
|---|---|---|---|---|---|---|---|---|
| Male/female | 10/10 | 6/4 | 10/5 | 8/5 | 6/4 | 7/3 | 9/4 | 8/4 |
| Age (years old) | 38.8 ± 9.8 | 40.7 ± 14.9 | 33.8 ± 9.4 | 38.0 ± 8.4 | 39.4 ± 13.2 | 50.1 ± 12.6 | 51.3 ± 13.1 | 50.2 ± 17.4 |
| Blood cell counts (109/L) | 7.3 ± 2.1 | 5.9 ± 0.6 | 5.8 ± 1.0 | 5.8 ± 3.4 | 4.3 ± 1.2 | 5.8 ± 3.4 | 5.0 ± 1.8 | 4.2 ± 1.8 |
| Hemoglobin (g/L) | 140 ± 12 | 151 ± 15 | 148 ± 23 | 144 ± 16 | 136 ± 32 | 144 ± 19 | 130 ± 31 | 90 ± 19 |
| Blood platelet (109/L) | 175 ± 57 | 173 ± 12.8 | 175 ± 12.1 | 158 ± 24.1 | 121.3 ± 15.4 | 154.3 ± 20.1 | 105.3 ± 16.7 | 70.2 ± 17.8 |
| ALT (U/L) | 26.3 ± 9.3 | 79.5 ± 42.0 | 95.3 ± 33.3 | 124.1 ± 29.0 | 91.7 ± 17.5 | 57.1 ± 14.3 | 91.8 ± 15.2 | 30.8 ± 10.1 |
| AST (U/L) | 23.5 ± 7.1 | 65.2 ± 23.8 | 69.4 ± 11.2 | 91.6 ± 21.5 | 92.75 ± 19.9 | 46.4 ± 19.7 | 67.2 ± 17.2 | 56.1 ± 12.6 |
| γ-GT (U/L) | 31.2 ± 5.7 | 37.0 ± 18.1 | 50.8 ± 38.4 | 76.9 ± 25.8 | 58.8 ± 28.3 | 63.2 ± 29.1 | 61.1 ± 19.2 | 37.9 ± 13.4 |
| ALP (U/L) | 68.0 ± 11.0 | 69.2 ± 24.4 | 79.8 ± 22.5 | 125.5 ± 46.8 | 94.6 ± 27.9 | 87.9 ± 11.6 | 83.6 ± 13.2 | 100 ± 15.5 |
| T-Bil (μmol/L) | 13.6 ± 5.3 | 27.9 ± 7.41 | 22.2 ± 8.04 | 26.9 ± 3.2 | 19.1 ± 2.3 | 12.9 ± 4.4 | 23.3 ± 8.3 | 68.6 ± 12.3 |
| D-Bil (μmol/L) | 5.0 ± 1.2 | 15.2 ± 5.0 | 6.5 ± 2.2 | 11.6 ± 6.1 | 8.2 ± 3.7 | 3.6 ± 1.1 | 7.5 ± 3.3 | 47.9 ± 9.1 |
| TP (g/L) | 74.6 ± 8.3 | 67.6 ± 8.8 | 68.6 ± 8.3 | 72.4 ± 6.2 | 68.7 ± 8.0 | 66.8 ± 7.5 | 66.3 ± 9.6 | 53.2 ± 5.8 |
| ALB (g/L) | 44.5 ± 3.2 | 40.7 ± 3.7 | 40.2 ± 4.7 | 41.5 ± 3.6 | 39.0 ± 5.1 | 39.1 ± 5.1 | 30.3 ± 8.6 | 22.3 ± 9.4 |
| TC (U/L) | 3.3 ± 0.4 | 4.4 ± 1.0 | 3.2 ± 0.3 | 3.6 ± 0.4 | 3.8 ± 1.1 | 3.6 ± 0.8 | 4.8 ± 1.2 | 3.4 ± 0.2 |
| TG (U/L) | 0.6 ± 0.1 | 1.0 ± 0.4 | 1.0 ± 0.1 | 1.7 ± 0.4 | 1.2 ± 0.4 | 1.1 ± 0.4 | 1.4 ± 0.2 | 1.3 ± 0.3 |
| AFP | 12 ± 1.2 | 18.7 ± 32.1 | 6.2 ± 4.1 | 8.0 ± 13.4 | 28.8 ± 34.8 | 99.2 ± 12.1 | 104.2 ± 11.1 | 31.5 ± 11.2 |
| INR | 0.8 ± 0.01 | 0.97 ± 0.09 | 1.0 ± 0.03 | 1.1 ± 0.08 | 1.05 ± 0.07 | 1.6 ± 0.06 | 1.7 ± 0.02 | 1.8 ± 0.08 |
| HBV-DNA (107 U/L) | — | 4.5 ± 1.1 | 13.1 ± 2.7 | 5.2 ± 2.1 | 3.1 ± 1.1 | 1.3 ± 0.2 | 0.9 ± 0.2 | 0.6 ± 0.3 |
| HBeAg-positive rate (%) | — | 30% | 80% | 58% | 60% | 40% | 38% | 33% |
CC: compensated cirrhosis; DC: decompensated cirrhosis; CHB: chronic hepatitis B.