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. 2021 Mar 9;181:113153. doi: 10.1016/j.bios.2021.113153

Table 2.

Reported SERS substrates studied for virus detection and the corresponding vibrational modes attributed to viral components.

Ref. Substrate Target virus Vibrational mode/component Peak assignment (cm−1)
Fan et al. (2010) Klarite (Au on Si) a variety of enveloped viruses: S–S stretch 540
Tyrosine (skeletal) 640
Adenine 720, 744
norovirus MNV4 Tyrosine 844
C–COO- stretch 921, 937, 943
Phenylalanine (symmetrical ring breathing) 1001
adenovirus MAD Phenlyalanine (in-plane C–H bending) 1018, 1022
C–N stretch 1047
C–N and C–C stretch 1129
Shanmukh et al. (2006) Ag nanorod adenovirus Guanine ~643–656
Adenine ~719–730
rhinovirus Tyrosine ~848–843
Phenylalanine ~1002
HIV CH2 deformation ~1448–1454
νaCOO Trp ~1523–1597
respiratory syncytial virus disulfide stretching 527, 546
C–N stretching 1044
CH2 deformation 1456
Zhang et al. (2019) Au/Cu hollow nanocones of microbowls (HNCMB) adenovirus type 5,
coxsackievirus type 3
carbohydrates for solids 1015
C–N stretching ~1041–1062