Table 2. Incidence rates and risk of MGs according to age, sex, region, and income status (2007–2017).
| Parameters | No. of patients with MG | No. of deaths | Duration (person-year) | Mortality rate (per 1,000) | HRa (95% CI) | P-value | |
|---|---|---|---|---|---|---|---|
| Total | 45,066 | 25,294 | 1,334,432.5 | 188.15 | |||
| Age, yr | |||||||
| 0–19 | 4,006 | 962 | 21,722.6 | 44.28 | 0.72 (0.67–0.78)b | < 0.001 | |
| 20–39 | 5,783 | 1,821 | 28,554.34 | 63.77 | Reference | ||
| 40–64 | 19,066 | 10,465 | 58,300.46 | 179.50 | 2.38 (2.26–2.50)b | < 0.001 | |
| ≥ 65 | 16,211 | 12,046 | 25,855.08 | 465.90 | 4.85 (4.62–5.10)b | < 0.001 | |
| Sex | |||||||
| Male | 23,725 | 14,295 | 65,977.22 | 216.66 | Reference | ||
| Female | 21,341 | 10,999 | 68,455.26 | 160.37 | 0.69 (0.67–0.71)c | < 0.001 | |
| Region | |||||||
| Metropolitan | 25,943 | 14,282 | 80,323.18 | 177.80 | Reference | ||
| City | 13,389 | 7,520 | 38,970.79 | 192.96 | 1.02 (0.99–1.05) | 0.101 | |
| Rural | 5,734 | 3,492 | 15,138.52 | 230.67 | 0.99 (0.96–1.03) | 0.814 | |
| Income | |||||||
| Low | 12,567 | 7,294 | 36,412.84 | 200.31 | 1.08 (1.05–1.12) | < 0.001 | |
| Middle | 19,976 | 11,037 | 61,534.87 | 179.36 | Reference | ||
| High | 12,523 | 6,963 | 36,484.78 | 190.84 | 0.91 (0.88–0.93) | < 0.001 | |
MG = malignant glioma, HR = hazard ratio, CI = confidence interval, TMZ = temozolomide.
aSex- and age-adjusted ratio; bSex-adjusted ratio; cAge-adjusted ratio.