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. 2021 Mar 2;36(9):e68. doi: 10.3346/jkms.2021.36.e68

Table 2. Incidence rates and risk of MGs according to age, sex, region, and income status (2007–2017).

Parameters No. of patients with MG No. of deaths Duration (person-year) Mortality rate (per 1,000) HRa (95% CI) P-value
Total 45,066 25,294 1,334,432.5 188.15
Age, yr
0–19 4,006 962 21,722.6 44.28 0.72 (0.67–0.78)b < 0.001
20–39 5,783 1,821 28,554.34 63.77 Reference
40–64 19,066 10,465 58,300.46 179.50 2.38 (2.26–2.50)b < 0.001
≥ 65 16,211 12,046 25,855.08 465.90 4.85 (4.62–5.10)b < 0.001
Sex
Male 23,725 14,295 65,977.22 216.66 Reference
Female 21,341 10,999 68,455.26 160.37 0.69 (0.67–0.71)c < 0.001
Region
Metropolitan 25,943 14,282 80,323.18 177.80 Reference
City 13,389 7,520 38,970.79 192.96 1.02 (0.99–1.05) 0.101
Rural 5,734 3,492 15,138.52 230.67 0.99 (0.96–1.03) 0.814
Income
Low 12,567 7,294 36,412.84 200.31 1.08 (1.05–1.12) < 0.001
Middle 19,976 11,037 61,534.87 179.36 Reference
High 12,523 6,963 36,484.78 190.84 0.91 (0.88–0.93) < 0.001

MG = malignant glioma, HR = hazard ratio, CI = confidence interval, TMZ = temozolomide.

aSex- and age-adjusted ratio; bSex-adjusted ratio; cAge-adjusted ratio.