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. 2021 Feb 23;8:632393. doi: 10.3389/fcvm.2021.632393

Table 7.

List of down-regulated circRNAs in CAD.

CircRNAs Samples Assessed cell line Association with clinical features Function References
circZNF609 Blood samples from (peripheral blood leukocytes) 330 patients with CAD and 209 control individuals RAW264.7 C-reactive protein levels, lymphocyte counts Its overexpression contributes to decreased expression of IL-6 and TNF-α and increased expression of IL-10 (66)
hsa_circ_0029589 Blood samples (PBMCs) from 24 patients with clinical presentation of chest pain, 16 patients with stable angina, and 28 patients with acute coronary syndrome Its overexpression decreased pyroptosis of macrophages (67)