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. 2021 Feb 23;13:629891. doi: 10.3389/fnagi.2021.629891

Figure 1.

Figure 1

Cognitive function of Alzheimer’s disease (AD) model mice. (A–C) The swimming distance, incubation period, and average swimming speed of the APP/PS1 group and Aβ25–35 group mice were studied in the Morris water maze (MWM) experiment with a visual platform. (D,E) The swimming distance and latency of the APP/PS1 group and the Aβ25–35 group in the MWM experiment with a hidden platform (WT vs. APP/PS1 group: *p < 0.05, **p < 0.01; WT vs. Aβ25–35 group: #p < 0.05, ##p < 0.01; n = 10). (F) Swimming path map of the APP/PS1 group and Aβ25–35 group mice in the water tank. (G) The number of platform crossings of the Aβ25–35 group and APP/PS1 group mice after removing the platform (*p < 0.05, **p < 0.01; “ns” means there is no significant difference; n = 10).