TABLE 4.
The time of onset and resolution of adverse events related to immune checkpoint inhibitors are depicted below.
Median time of onset in months (95% CI) | Median time to resolution in months (95% CI) | |
---|---|---|
Hepatitis | 1.47 (0–4.0) | 0.6 (0–2) |
Pneumonitis | 2.53 (0.9–4.2) | 24 days (resolved in 2 patients out of 7) |
Colitis | 3.9 (0–8) | 0.8 (0–2.3) |
Nephritis | 0.5 (0–1.6) | 8.8 (1–16.5) |
Adrenal insufficiency | 3.1 (0–7.5) | Resolved in 1 patient after 120 days |
Fatigue | 1.4 (0.1–2.6) | 5.8 (1.9–10) |
Anorexia | 1.3 (1.0–1.6) | 2.3 (1.4–3.2) |
Abbreviations: CI, confidence interval.