TABLE 1.
Summary of all the basic characteristics of the included studies
| First author | Year | Country | Number of patients | Treatment | Median age | Male (%) | Current or former smoking (%) |
|---|---|---|---|---|---|---|---|
| M. Montopoli | 2020 | Italy | 118 | Endocrinotherapy | 73 | 100 | NR |
| Lennard Y W Lee | 2020 | UK | 800 | Chemotherapy | 69 | 56 | NR |
| Mengyuan Dai | 2020 | China | 105 | Chemotherapy Targeted therapy Radiotherapy Surgery Immunotherapy Endocrinotherapy | 61 | 56 | 33 |
| Jia Luo | 2020 | USA | 69 | Chemotherapy Targeted therapy Immunotherapy | 69 | 48 | 64 |
| Fan Yang | 2020 | China | 52 | Chemotherapy Surgery Immunotherapy | 63 | 53.8 | NR |
| Jianbo Tian | 2020 | China | 232 | Chemotherapy Targeted therapy Radiotherapy Surgery Immunotherapy | 64 | 51 | 6 |
| Kunyu Yang | 2020 | China | 205 | Chemotherapy Targeted therapy Radiotherapy Surgery Immunotherapy | 63 | 47 | NR |
| Nicole M Kuderer | 2020 | USA Canada Spain | 928 | Chemotherapy Radiotherapy Surgery | 66 | 50 | 40 |
| Jacobo Rogado | 2020 | Spain | 17 | Chemotherapy Targeted therapy Surgery Immunotherapy | 68 | 76.5 | NR |
| Perrine Vuagnat | 2020 | France | 59 | Chemotherapy Targeted therapy Radiotherapy Surgery Endocrinotherapy | 58 | NR | NR |
| Vikas Mehta | 2020 | USA | 218 | Chemotherapy Radiotherapy Immunotherapy | 69 | 58 | NR |
| Elisa Maria Stroppa | 2020 | Italy | 25 | Chemotherapy Immunotherapy | 72 | 80 | 52 |
| J Rogado | 2020 | Spain | 45 | Chemotherapy | 71 | 66.7 | NR |
| Giorgio Bogani | 2020 | Italy | 19 | Chemotherapy Surgery | 65 | NR | NR |
| Jia Luo | 2020 | USA | 102 | Chemotherapy Targeted therapy Immunotherapy | 68 | 48 | 27 |
| B Russell | 2020 | UK | 156 | Chemotherapy Targeted therapy Immunotherapy | 67 | 58 | 32 |