TABLE 2.
Clinicopathological variables associated with sialyl‐Tn expression in malignant nipple fluid cytology
| Variable | sTn (+) | sTn (−) | Total | p value |
|---|---|---|---|---|
| Tumor type | ||||
| DCIS | 21 | 24 | 45 | 0.371 |
| IDC | 18 | 30 | 48 | |
| Histological grade of IDC | ||||
| I | 3 | 6 | 9 | 0.927 |
| II | 9 | 12 | 21 | |
| III | 6 | 12 | 18 | |
| Nuclear grade of DCIS | ||||
| Low | 3 | 6 | 9 | 0.192 |
| Intermediate | 6 | 12 | 18 | |
| High | 12 | 8 | 18 | |
| HER‐2 on IDC | ||||
| Positive | 15 | 9 | 24 | 0.039 |
| Negative | 3 | 21 | 24 | |
| ER status on IDC | ||||
| Positive | 9 | 12 | 21 | 0.696 |
| Negative | 9 | 18 | 27 | |
| PR status on IDC | ||||
| Positive | 6 | 15 | 21 | 0.515 |
| Negative | 12 | 15 | 27 | |
| Tumor size | ||||
| <2 cm | 30 | 39 | 69 | 0.609 |
| ≥2 cm | 9 | 15 | 24 | |
sTn(+): positive sTn expression; sTn(‐): negative sTn expression; Total: total number of patients with malignant nipple fluid (bold).