Table 3.
Number (n) and percentage (%) of categories of pregnancy and delivery outcomes first live-born child of female POPS-35 participants
| Characteristics | First pregnancy of POPS-35 women | First pregnancy of PeriNed women < 35 years | p value |
|---|---|---|---|
| Total N | 118 | 66,561 | |
| Conception, n (%) | 0.002 | ||
| Spontaneous | 102 (86%) | 49,349 (94%) | |
| Assisted reproductive technology | 16 (14%) | 3421 (6%) | |
| Unknown | 13,791 | ||
| Pregnancy complications, n (%) | |||
| Hypertension during pregnancy | 28* (24%) | 5980 (9%) | < 0.001 |
| (Pre)-eclampsia~ | 17 (14%) | 279 (0.4%) | < 0.001 |
| Gestational diabetes | 6 (5%) | 1709 (3%) | 0.08 |
| Delivery outcome n (%) | 66,177 | ||
| Delivery mode | 0.053 | ||
| Vaginal | 66 (56%) | 42,929 (66%) | |
| Instrumental | 25 (21%) | 10,042 (16%) | |
| Cesarean | 27 (23%) | 11,696 (18%) | |
| Unknown | 1510 | ||
| Complications | |||
| Placental pathology | 5 (4%) | 2096 (3%) | 0.51 |
| Perinatal outcomes in offspring | |||
| Gestational age, m (sd) | 39.3 (1.9) | 38.9 (2.2) | 0.04 |
| Birth weight, m (sd) | 3270.8 (601.4) | 3304.5 (596.6) | 0.54 |
| Low birth weight (< 2500 g), n (%) | 12 (10%) | 5216 (8%) | 0.36 |
| Preterm birth (< 37 weeks), n (%) | 9 (8%) | 6016 (9%) | 0.58 |
| NICU admission of child, n (%) | 13 (11%) | 1094 (2%) | <0.001 |
*One woman already knew she had high blood pressure before the pregnancy
~In POPS-35 questionnaire: have you had pre-eclampsia/pregnancy poisoning/high blood pressure with protein in the urine/high blood pressure with convulsions (resembles an epileptic attack); (pre-)eclampsia if one of these symptoms indicated. PeriNed warns for underreportage of pregnancy complications, such as (pre-)eclampsia