Table 1.

Comparison between extracellular vesicles

Types	Exosomes	Microvesicles	Apoptotic bodies	References
Origin	Endocytic pathway	Plasma membrane	Plasma membrane	[1, 9]
Size	30–150 nm	50–1000 nm	500–2000 nm
Function	Intercellular communication	Intercellular communication	Facilitate phagocytosis
Markers	Alix, Tsg101, tetraspanins (CD81, CD63, CD9), flotillin	Integrins, selectins, CD40	Annexin V, phosphatidylserine
Contents	Proteins and nucleic acids (mRNA, miRNA, and other non-coding RNAs)	Proteins and nucleic acids (mRNA, miRNA, and other non-coding RNAs)	Nuclear fractions, cell organelles