Table 8.
Final etiology (no. of cases) |
% of cases with final etiology among most abundant taxa | % of cases with final etiology not among | ||||||||
---|---|---|---|---|---|---|---|---|---|---|
Placenta | Lung–liver pool | Highest abundance ≥1 site | Highest, 2nd or 3rd highest ≥1 site | Highest abundance neither site | Three most abundant neither site | |||||
Highest | Highest or 2nd highest | Highest, 2nd or 3rd highest | Highest | Highest or 2nd highest | Highest, 2nd or 3rd highest | |||||
S. aureus (3) | 100 | 100 | 100 | 67 | 67 | 67 | 100 | 100 | 0 | 0 |
T. pyogenes (8) | 38a | 38a | 63a | 50 | 50 | 75 | 63 | 75 | 38 | 25 |
L. monocytogenes (2) | 100 | 100 | 100 | 100 | 100 | 100 | 100 | 100 | 0 | 0 |
B. licheniformis (4) | 50 | 100 | 100 | 25 | 25 | 25 | 75 | 100 | 25 | 0 |
Streptococcus sp. (1) | 100 | 100 | 100 | 0 | 100 | 100 | 100 | 100 | 0 | 0 |
E. coli (8) | 63 | 63 | 63 | 13 | 25 | 25 | 63 | 63 | 38 | 38 |
L. garvieae (2) | 50 | 50 | 50 | 0 | 50 | 50 | 50 | 50 | 50 | 50 |
Aeromonas sp. (1) | 0 | 0 | 0 | 0 | 0 | 100 | 0 | 100 | 100 | 0 |
K. pneumonia (1) | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 100 | 100 |
Average accordance in % | 56 | 56 | 64 | 28 | 46 | 60 | 61 | 76 | NA | NA |
NA, not applicable.
Placenta was not available in three of eight cases.
Level of accordance between the final etiology and the most sequencing abundant taxa in the placenta and/or the lung–liver pool. The final etiology was determined based on a combination of diagnostic methods (bacterial culture, histopathology, and 16S rDNA amplicon sequencing–based FISH).