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. 2021 Mar 8;11:5426. doi: 10.1038/s41598-021-84641-8

Table 3.

Proportion of detection of Methanobrevibacter smithii in children according to age and nutritional status excluding children with diarrhea, emesis and gastroenteritis—weighted data (n = 215).

Age Total (n = 212) Healthy controls (n = 126) Severe acute malnutrition (n = 89) Marasmus (n = 105) Kwashiorkor (n = 7) Marasmic-kwashiorkor (n = 9) p-valuea
0–6 months 6/31 (18.7%) 6/18 (33.3%) 0/13 (0.0%) 0/13 (0.0%) 0.09
7–12 months 16/93 (19.5%) 14/57 (24.6%) 2/36 (6.5%) 2/35 (5.7%) 0/1 (0.0%) 0.05
13–24 months 14/69 (20.5%) 12/37 (32.4%) 2/32 (4.9%) 2/25 (8.0%) 0/6 (0.0%) 0/1 (0.0%) 0.01
 > 24 months 13/22 (52%) 13/14 (92.9%) 0/8 (0.0%) 0/2 (0.0%) 0/0 (0.0%) 0/6 (0.0%) 0.006
Overall 49/215 (25.1%) 45/126 (35.7%) 4/89 (4.5%) 4/75 (5.3%) 0/7 (0.0%) 0/7 (0.0%)  < 0.0001

aWeighted logistic regression comparing the proportion of M. smithii positive samples in severely malnourished children compared to healthy controls.