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. 2021 Feb 23;10:620550. doi: 10.3389/fonc.2020.620550

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Copyright © 2021 Nie, Zhang, He, Wang, Wan, Wang and Han

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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LncRNA XLOC_012370 interacts with miR-140-5p. (A) Bioinformatic target prediction was performed with three online tools. (B) Binding situation between XLOC_012370 and miR-140-5p verified using RNA pull-down. n=3, *P < 0.05, **P < 0.01. (C) Luciferase assay was performed in the relationship between XLOC_012370 and miR-140-5p. n=3, *P < 0.05. (D) Pearson analysis of the correlation of miR‐140‐5p with XLOC_012370 expression in tumor tissues. n=30. (E) Co-localization between XLOC_012370 and miR-140-5p was revealed by fluorescence in situ hybridization. n.s. means not significant.