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. 2021 Feb 23;8:608959. doi: 10.3389/fmed.2021.608959

Table 2.

Perceptions of respondents on COVID-19 and correlation with attitude toward participation in COVID-19 clinical trials.

Do you agree with the following statements? (Yes/no) No. of “yes” respondents of the total sample (%) (N = 1,576) Attitude toward participating in a clinical trial Rho (P-value) P-value*
Positive (%) (n = 909) Negative (%) (n = 667)
The goal of conducting a clinical trial on a vaccine or drug against COVID-19 is to determine its safety and efficacy in humans. 1,464 (93.4) 859 (94.8) 605 (91.4) 0.06 (0.02) ** 0.01
Before conducting a clinical trial on either a drug or a vaccine for COVID-19, its safety and effectiveness should first be tested in animals to ensure their safety in humans. 1,352 (86.3) 784 (86.8) 568 (85.7) −0.01 (0.71) 0.51
When a vaccine for COVID-19 becomes available, I will not take it unless I am sure it is effective. 969 (61.9) 524 (57.8) 445 (67.5) 0.16 (<0.001) <0.001
When a drug for COVID-19 becomes available, I will not take it unless I am sure it is effective. 925 (59.1) 493 (54.5) 432 (65.5) 0.15 (<0.001) <0.001
Participating in a clinical trial on a vaccine for COVID-19 will increase my risk of contracting it. 447 (28.5) 217 (24.0) 230 (34.7) 0.14 (<0.001) <0.001
I am worried that I will contract COVID-19. 978 (62.3) 564 (62.2) 414 (62.4) −0.003 (0.31) 0.92
I am worried a family member (s) would contract COVID-19. 1,340 (85.6) 779 (86.0) 561 (85.0) −0.02 (0.43) 0.59
A newly developed vaccine or drug for COVID-19 will be exploited commercially. 1,017 (65.0) 567 (62.7) 450 (68.2) 0.08 (0.001) 0.02
A newly developed vaccine or drug for COVID-19 will be exploited politically. 983 (62.8) 559 (61.6) 424 (64.4) 0.05 (0.04) 0.26
Once a treatment for COVID-19 is made available, it will be affordable for most. 647 (41.3) 409 (45.1) 238 (36.1) 0.08 (0.002) <0.001
Once a vaccine for COVID-19 is made available, it will be affordable for most. 627 (40.0) 392 (43.2) 235 (35.7) 0.08 (0.001) 0.003
Interest in COVID-19 is exaggerated in general. 563 (35.9) 318 (35.1) 245 (37.1) −0.01 (0.60) 0.40
Contracting COVID-19 is closely linked to death. 144 (9.2) 90 (9.9) 54 (8.2) 0.05 (0.03) 0.23
*

P-value is based on Chi-square test.

**

Bold values indicate significant P values (< 0.05).