TABLE 3.
Logistic regression identifying factors associated with receipt of multimodal therapy versus non-standard therapy among cN3c patients, National Cancer Data Base 2004–2014 (N = 1480; events = 1122)
| OR (95% CI) | p value | Overall p value | |
|---|---|---|---|
| Age | 0.96 (0.95–0.97) | < 0.001 | < 0.001 |
| CDCC score | |||
| 0 | -REF- | 0.13 | |
| 1 | 0.73 (0.53–1.01) | 0.06 | |
| ≥ 2 | 0.70 (0.37–1.35) | 0.29 | |
| ER | |||
| Positive | -REF- | 0.39 | |
| Negative | 1.16 (0.82–1.65) | 0.39 | |
| PR | |||
| Positive | -REF- | 0.71 | |
| Negative | 0.93 (0.65–1.34) | 0.71 | |
| Histology | |||
| Invasive lobular | -REF- | 0.17 | |
| Invasive ductal | 0.77 (0.53–1.13) | 0.18 | |
| Facility type | |||
| Academic | -REF- | 0.03 | |
| Community | 0.97 (0.55–1.71) | 0.92 | |
| Comprehensive | 1.53 (1.11–2.10) | 0.009 | |
| Integrated network | 1.53 (0.97–2.40) | 0.07 | |
| Facility location | |||
| West | -REF- | 0.20 | |
| Midwest | 1.24 (0.85–1.83) | 0.27 | |
| Northeast | 0.85 (0.56–1.29) | 0.45 | |
| South | 0.94 (0.64–1.37) | 0.74 | |
| Hospital volume | |||
| Low-volume | -REF- | 0.77 | |
| Moderate-volume | 0.99 (0.68–1.43) | 0.95 | |
| High-volume | 1.11 (0.75–1.64) | 0.62 | |
| Income | |||
| ≥ 35,000 | -REF- | 0.06 | |
| < 35,000 | 0.77 (0.59–1.01) | 0.06 | |
| Insurance | |||
| Not insured | -REF- | < 0.001 | |
| Government | 1.83 (1.04–3.24) | 0.04 | |
| Private | 2.81 (1.64–4.82) | < 0.001 |
The model has accounted for the correlation of patients treated at the same hospital