Table 2:
Patients characteristics in PDAC patients with an unresectable disease
| Characteristics | Total | LAMC2 expression | |||
|---|---|---|---|---|---|
| n = 51 | Low (n = 27) | High (n = 24) | P-valuea | ||
| Age, years | 0.55 | ||||
| < 65, n (%) | 17 | 10 (37.0) | 7 (29.2) | ||
| ≥ 65, n (%) | 34 | 17 (63.0) | 17 (70.8) | ||
| Gender | 0.20 | ||||
| Male, n (%) | 24 | 15 (55.6) | 9 (37.5) | ||
| Female, n (%) | 27 | 12 (44.4) | 15 (62.5) | ||
| CA19-9 (U/mL) | 0.43b | ||||
| < 37, n (%) | 7 | 5 (18.5) | 2 (8.3) | ||
| ≥ 37, n (%) | 44 | 22 (81.5) | 22 (91.7) | ||
| Tumor size (mm) | 0.44 | ||||
| < 40, n (%) | 22 | 13 (48.1) | 9 (37.5) | ||
| ≥ 40, n (%) | 29 | 14 (51.9) | 15 (62.5) | ||
| Locally or Metastasis | 0.86 | ||||
| Locally advanced | 9 | 5 (18.5) | 4 (16.7) | ||
| Distal metastasis | 42 | 22 (81.5) | 20 (83.3) | ||
| Location | 0.66 | ||||
| Head | 16 | 8 (29.6) | 8 (33.3) | ||
| Body | 26 | 13 (48.1) | 13 (54.2) | ||
| Tail | 9 | 6 (22.3) | 3 (12.5) | ||
| site of metastasis | 0.34 | ||||
| Liver | 28 | 16 (66.7) | 12 (50.0) | ||
| Lung | 8 | 5 (20.9) | 3 (12.5) | ||
| Peritoneum | 5 | 1 (4.1) | 4 (16.7) | ||
| Lymph node | 6 | 2 (8.3) | 4 (16.7) | ||
| Other | 1 | 0 (0.0) | 1 (4.1) | ||
| No. of metastatic sites | 0.46 | ||||
| 0 | 10 | 5 (18.5) | 5 (20.9) | ||
| 1 | 36 | 20 (74.1) | 16 (66.7) | ||
| 2 | 3 | 2 (7.4) | 1 (4.1) | ||
| 3 | 2 | 0 (0.0) | 2 (8.3) | ||
a
Chi-square test
b
Fisher’s exact test