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. 2021 Mar 8;11:5405. doi: 10.1038/s41598-021-84860-z

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© The Author(s) 2021

Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

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689 diseases of men or women were categorised as acute, chronic, infectious, injuries, or symptoms of unknown cause (separate plots), and grouped by the number of cases (horizontal axes). We considered: whether associations were statistically significant at the 0.05 level after a Bonferroni multiple-testing adjustment?—no (orange), or if yes, whether proportional hazards test did (green) or did not (yellow) pass. The median number of cases was 214. The vertical axis for acute diseases has a different scale.