Table 3.
Subgroup analysis with univariate cox regression analyses for OS in the surgery group.
| Variables | Univariate analysis | |
|---|---|---|
| HR (95% CI) | P values † | |
| Gender | ||
| Male vs. Female | 0.862 (0.419–1.775) | 0.687 |
| Age | ||
| ≥ 71.3 vs. < 71.3 | 1.696 (0.827–3.480) | 0.150 |
| Stage | ||
| I, II vs. III, IV | 1.861 (0.885–3.914) | 0.101 |
| T stage | ||
| T1,2 vs. 3,4 | 1.567 (0.764–3.211) | 0.220 |
| N classification | ||
| N0, 1 vs. N2, 3 | 2.039 (0.933–4.457) | 0.074 |
| NLR | ||
| ≥ 3.59 vs. < 3.59 | 2.181 (1.021–4.662) | 0.044* |
| SIRI | ||
| ≥ 1.19 vs. < 1.19 | 1.981 (0.941–4.168) | 0.072 |
| SII | ||
| ≥ 823.1vs. < 823.1 | 2.623 (1.262–5.449) | 0.010* |
| LMR | ||
| ≥ 5.0 vs. < 5.0 | 0.567 (0.275–1.168) | 0.124 |
| CAR | ||
| ≥ 0.032 vs. < 0.032 | 2.262 (1.087–4.705) | 0.029* |
| Pathological ENE | ||
| Present or absent | 9.360 (3.724–23.526) | < 0.001** |
| Positive LN counts | ||
| ≥ 2 vs. < 2 | 3.043 (1.423–6.507) | 0.004** |
†By Cox proportional hazards regression.
*P < 0.05 Statistically significant difference, **P < 0.01 Statistically significant difference.
NLR, neutrophil lymphocyte ratio; SIRI, systemic inflammation response index; LMR, lymphocyte monocyte ratio; SII, systemic immune-inflammation index; CAR, C-reactive protein/albumin ratio; ENE, Extra nodal extension; LN, Lymph node.