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. 2021 Mar 8;11:5412. doi: 10.1038/s41598-021-84887-2

Table 1.

Knock-in mouse lines backcrossed to S4.

Line Feature % S4a PMID Reference
PV-IRES-Cre Marks PV neurons 99.8 15836427 Hippenmeyer, 200545
SST-IRES-Cre Marks SST neurons 99.8 21943598 Taniguchi, 201146
Gad2-IRES-Cre Marks GABA neurons 99.8 21943598 Taniguchi, 201146
vGlut2-IRES-Cre Marks glutamatergic neurons 100 21745644 Vong, 201147
Calb2-IRES-Cre Marks calbindin2 neurons 91.2b 2194398 Taniguchi, 201146
Slc1a3-2A-CreERT2 Marks astrocytes 100c This report This report
Cx3cr1-CreERT2 Marks brain macrophages 91.0b 23273845 Yona, 201348
LSL-Tagger Tagger (reporter, IP tool) 98.6b 31393866 Kaczmarczyk, 201925
Rpl22-HA RiboTag (reporter, IP tool) 99.8 19666516 Sanz, 200949
HdhQ200 Disease model 100 11152661 Lin, 200150

PV parvalbumin, SST somatostatin, GABA gamma-aminobutyric acid, IP immunoprecipitation.

aBased on genotyping 347 loci across the genome that discriminate S4 from B6.

bThese lines were backcrossed four more generations after genotyping analysis.

cThis line was made directly in S4.