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. 2021 Feb 23;12:591223. doi: 10.3389/fneur.2021.591223

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Copyright © 2021 Li and Zhang.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Venlafaxine (VLX) decreased the surface expression of GABA_A receptor α5 in mice exposed to isoflurane (ISO). (A) The effect of VLX on the surface expression of α5 receptor in mice exposed to ISO. (B) The effect of VLX on the total expression of α5 receptor in mice exposed to ISO. Data were expressed as mean ± SEM. ^*p < 0.05 compared to control; ^#p < 0.05 compared to ISO, n = 6.