Table 2. Unadjusted and adjusted prognostic role of O-A interval on disease progression.
| Variables | Univariate regression | Multivariate regression | |||
|---|---|---|---|---|---|
| OR (95% CI) | P value | OR (95% CI) | P value | ||
| O-A interval (≤7 vs. >7 d) | 2.93 (1.32–6.55) | 0.009 | 3.44 (1.20–9.83) | 0.021 | |
| Age (>60 vs. ≤60 y) | 5.00 (2.15–11.64) | < 0.001 | 2.22 (0.72–6.87) | 0.166 | |
| Comorbidity (any vs. none) | 3.48 (1.54–7.83) | 0.003 | 2.80 (0.88–8.91) | 0.081 | |
| Neutrophil-to-lymphocyte ratio | 1.08 (1.00–1.06) | 0.043 | 1.03 (0.92–1.16) | 0.560 | |
| Thrombin time, s | 1.11 (0.94–1.31) | 0.206 | |||
| Total bilirubin, mmol/L | 1.08 (0.97–1.20) | 0.170 | |||
| Albumin, g/L | 0.93 (0.85–1.00) | 0.061 | |||
| Blood urea nitrogen, mmol/L | 1.28 (1.06–1.55) | 0.010 | 1.31 (0.93–1.83) | 0.120 | |
| Lactate dehydrogenase, IU/L | 1.01 (1.00–1.01) | 0.001 | 1.01 (1.00–1.01) | 0.010 | |
Complete-case analysis was adopted in multivariate logistic regression model. 106/118 cases were included in multivariate analysis, and 34/106 cases experienced disease deterioration. O-A interval, the interval between onset and admission; OR, odds ration; CI, confidence interval.