Table 2. Associations between clinicopathological features and skip metastasis.
| Categories | Variables | No. of studies | Pooled data | Heterogeneity | ||||
|---|---|---|---|---|---|---|---|---|
| HR | 95% CI | P | I2 (%) | Ph | ||||
| Differentiation | Well + moderate/poor | 6 | 1.06 | 0.86–1.30 | 0.574 | 0 | 0.532 | |
| Histology | LUAD/LUSC | 15 | 0.85 | 0.70–1.04 | 0.113 | 57.5 | 0.003 | |
| Pleural invasion | Existence/non | 3 | 0.86 | 0.67–1.10 | 0.223 | 0 | 0.658 | |
| Smoking | Smoking/non | 6 | 1.00 | 0.65–1.56 | 0.985 | 82.9 | 0 | |
| Diameter | <3 cm/>3 cm | 5 | 0.96 | 0.80–1.15 | 0.645 | 48.8 | 0.099 | |
| Tumor location | Upper/lower | 9 | 1.16 | 1.00–1.34 | 0.044 | 39.8 | 0.102 | |
DFS, disease free survival; RFS, recurrence free survival; LUAD, lung adenocarcinoma; LUSC, lung squamous carcinoma; HR, hazard ratio; CI, confidence interval; Ph, P value for heterogeneity.