Table 2. Baseline laboratory findings of patients with COVID–19.
| Parameter | Normal range | All patients (n=196) | Severe group (n=45) | Non-severe group (n=151) | P values |
|---|---|---|---|---|---|
| White blood cell count, ×109/L | 3.5–9.5 | 4.6 [3.8–5.7] | 4.5 [3.9–6.2] | 4.7 [3.8–5.7] | 0.271 |
| Neutrophil count, ×109/L | 1.8–6.3 | 2.9 [2.4–3.9] | 3.5 [2.8–4.7] | 2.8 [2.3–3.7] | <0.001* |
| Lymphocyte count, ×109/L | 1.1–3.2 | 1.1 [0.8–1.4] | 0.8 [0.6–1.0] | 1.2 [0.9–1.5] | <0.001* |
| D-dimer, μg/mL | 0–0.5 | 0.4 [0.3–0.8] | 0.8 [0.5–1.2] | 0.4 [0.3–0.5] | <0.001* |
| Alanine aminotransferase, U/L | 7–40 | 24 [16–36] | 26 [19–36] | 22 [15–35] | 0.065 |
| Aspartate aminotransferase, U/L | 13–35 | 26 [20–35] | 31 [26–51] | 24 [19–33] | <0.001* |
| Lactate dehydrogenase, U/L | 120–250 | 242 [204–309] | 342 [290–454] | 228 [199–261] | <0.001* |
| Total bilirubin, μmol/L | 3.4–20.5 | 8.2 [6.7–10.9] | 9.0 [7.8–12.4] | 7.9 [6.6–10.2] | 0.018* |
| Albumin, g/L | 40.0–55.0 | 40.7 [37.9–42.7] | 37.8 [34.2–39.7] | 41.2 [39.2–43.4] | <0.001* |
| Serum creatinine, μmol/L | Male: 53–106 | ||||
| Increased | Female: 44–97 | 17 (8.7) | 6 (13.3) | 11 (7.3) | 0.230 |
| Serum troponin I, ng/mL | 0–0.040 | 0.022 [0.012–0.041] | 0.036 [0.019–0.062] | 0.019 [0.011–0.035] | <0.001* |
| Serum myoglobin, ng/mL | 0–48.8 | 7.3 [3.2–17.5] | 27.6 [8.4–63.7] | 5.4 [2.7–11.5] | <0.001* |
| Procalcitonin, ng/mL | 0–0.05 | 0.04 [0.02–0.07] | 0.07 [0.05–0.15] | 0.03 [0.02–0.06] | <0.001* |
| PaO2, KPa | 10.0–14.0 | 12.2 [10.5–14.6] | 11.1 [9.3–14.3] | 12.5 [11.0–14.6] | 0.022* |
| SaO2, % | 91.9–99.0 | 97.5 [96.2–98.5] | 96.7 [94.3–98.5] | 97.6 [96.6–98.5] | 0.020* |
| C-reactive protein, mg/L | <3.0 | 15.1 [5.3–33.5] | 38.7 [26.8–88.2] | 11.0 [4.3–22.2] | <0.001* |
| CD4+ T cell count, cell/μL | 410–1590 | 406 [261–592] | 216 [137–397] | 453 [310–633] | <0.001* |
Continuous variables are presented as median (interquartile range), and dichotomous variables are presented as numbers of patients, with percentages in parentheses. *, P<0.05; P values are from Fisher’s exact test or Wilcoxon rank-sum test when comparing the severe group with the non-severe group; COVID-19, coronavirus disease 2019; PaO2, partial pressure of oxygen; SaO2, arterial oxygen saturation; CD4, cluster of differentiation 4.