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. 2021 Feb;9(3):216. doi: 10.21037/atm-20-2464

Table 2. Baseline laboratory findings of patients with COVID–19.

Parameter Normal range All patients (n=196) Severe group (n=45) Non-severe group (n=151) P values
White blood cell count, ×109/L 3.5–9.5 4.6 [3.8–5.7] 4.5 [3.9–6.2] 4.7 [3.8–5.7] 0.271
Neutrophil count, ×109/L 1.8–6.3 2.9 [2.4–3.9] 3.5 [2.8–4.7] 2.8 [2.3–3.7] <0.001*
Lymphocyte count, ×109/L 1.1–3.2 1.1 [0.8–1.4] 0.8 [0.6–1.0] 1.2 [0.9–1.5] <0.001*
D-dimer, μg/mL 0–0.5 0.4 [0.3–0.8] 0.8 [0.5–1.2] 0.4 [0.3–0.5] <0.001*
Alanine aminotransferase, U/L 7–40 24 [16–36] 26 [19–36] 22 [15–35] 0.065
Aspartate aminotransferase, U/L 13–35 26 [20–35] 31 [26–51] 24 [19–33] <0.001*
Lactate dehydrogenase, U/L 120–250 242 [204–309] 342 [290–454] 228 [199–261] <0.001*
Total bilirubin, μmol/L 3.4–20.5 8.2 [6.7–10.9] 9.0 [7.8–12.4] 7.9 [6.6–10.2] 0.018*
Albumin, g/L 40.0–55.0 40.7 [37.9–42.7] 37.8 [34.2–39.7] 41.2 [39.2–43.4] <0.001*
Serum creatinine, μmol/L Male: 53–106
   Increased Female: 44–97 17 (8.7) 6 (13.3) 11 (7.3) 0.230
Serum troponin I, ng/mL 0–0.040 0.022 [0.012–0.041] 0.036 [0.019–0.062] 0.019 [0.011–0.035] <0.001*
Serum myoglobin, ng/mL 0–48.8 7.3 [3.2–17.5] 27.6 [8.4–63.7] 5.4 [2.7–11.5] <0.001*
Procalcitonin, ng/mL 0–0.05 0.04 [0.02–0.07] 0.07 [0.05–0.15] 0.03 [0.02–0.06] <0.001*
PaO2, KPa 10.0–14.0 12.2 [10.5–14.6] 11.1 [9.3–14.3] 12.5 [11.0–14.6] 0.022*
SaO2, % 91.9–99.0 97.5 [96.2–98.5] 96.7 [94.3–98.5] 97.6 [96.6–98.5] 0.020*
C-reactive protein, mg/L <3.0 15.1 [5.3–33.5] 38.7 [26.8–88.2] 11.0 [4.3–22.2] <0.001*
CD4+ T cell count, cell/μL 410–1590 406 [261–592] 216 [137–397] 453 [310–633] <0.001*

Continuous variables are presented as median (interquartile range), and dichotomous variables are presented as numbers of patients, with percentages in parentheses. *, P<0.05; P values are from Fisher’s exact test or Wilcoxon rank-sum test when comparing the severe group with the non-severe group; COVID-19, coronavirus disease 2019; PaO2, partial pressure of oxygen; SaO2, arterial oxygen saturation; CD4, cluster of differentiation 4.