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Overexpression of Cx43 reversed the protective effect of normal glucose in GDM-HUVECs. (A) Cx43; (B) ICAM-1, VCAM-1 protein expression; (C) cell adhesion. Data are presented as mean ± SEM; n=5, *, P<0.05 vs. GDM, #, P<0.05 vs. GDM-G. Scale bar in C: ×200 and ×400. Cx43, Connexin 43; GDM, gestational diabetes mellitus; ICAM-1, intercellular cell adhesion molecule-1; VCAM-1, vascular cell adhesion protein 1; RA, retinoic acid (Cx43 protein expression fortifier).
