Table 1. Demographics, bleeding scores, disease duration and routine haematological parameters in primary ITP, SLE-TP, SLE-NTP patients, and healthy controls.
Variables | ITP (n=17) | SLE-TP (n=17) | SLE-NTP (n=19) | Controls (n=10) |
---|---|---|---|---|
Age, median [range] | 52 [23–71] | 36 [21–61] | 36 [17–66] | 40.5 [24–68] |
Sex | ||||
Female | 10 | 15 | 15 | 6 |
Male | 7 | 2 | 4 | 4 |
Bleeding score at initial diagnosis, mean [range] | 2.76 [1–5]# | 0.94 [0–5] | – | – |
Duration of disease (thrombocytopenia >12 months) | 7/17 | 4/17 | – | – |
Platelet count (×109/L), median [range] | 9 [1–22] | 66 [29–95] | 183 [104–327] | 247 [185–309] |
Absolute lymphocyte count (×109/L), mean ± SD | 1.83±0.58# | 0.91±0.67* | 1.03±0.53* | 2.14±0.39 |
Absolute neutrophil count (×109/L), mean ± SD | 5.83±3.17#* | 3.29±2.62 | 4.32±2.47 | 3.3±1.24 |
*, P<0.05 compared to health control; #, P<0.05 compared to SLE-TP. ITP, immune thrombocytopenia; SLE-TP, systemic lupus erythematosus-associated thrombocytopenia; SLE-NTP, SLE without thrombocytopenia.