Table 4. Spearman correlations among inflammatory markers and age.
| Variables | Age | PrePLR | PreNLR | PreRDW | IL-6 | CRP |
|---|---|---|---|---|---|---|
| (a) CCSVI with non-immunological etiology (n=98) | ||||||
| PrePLR | −0.094 | |||||
| PreNLR | −0.008 | 0.306* | ||||
| PreRDW | −0.091 | −0.005 | 0.175 | |||
| IL-6 | 0.090 | 0.105 | 0.324* | 0.107 | ||
| CRP | 0.062 | 0.213* | 0.196 | 0.224* | 0.339* | |
| NSE | −0.028 | −0.245* | −0.084 | 0.070 | 0.201 | 0.004 |
| (b) CCSVI with suspected/subclinical autoimmune disease (n=116) | ||||||
| PrePLR | 0.139 | |||||
| PreNLR | 0.137 | 0.465* | ||||
| PreRDW | 0.008 | −0.231* | −0.045 | |||
| IL-6 | 0.202 | 0.061 | 0.275* | 0.161 | ||
| CRP | 0.166 | 0.249* | 0.144 | −0.019 | 0.291* | |
| NSE | −0.124 | −0.029 | −0.090 | −0.002 | −0.101 | 0.118 |
| (c) CCSVI with confirmed autoimmune disease (n=41) | ||||||
| PrePLR | −0.194 | |||||
| PreNLR | 0.188 | 0.148 | ||||
| PreRDW | 0.049 | −0.045 | 0.055 | |||
| IL-6 | 0.388* | −0.117 | 0.241 | 0.163 | ||
| CRP | 0.069 | −0.268 | −0.031 | 0.108 | 0.477* | |
| NSE | 0.095 | −0.188 | −0.197 | −0.065 | 0.005 | 0.083 |
*, statistically significant at P<0.05. PreNLR, neutrophil to lymphocyte ratio on admission; PrePLR, platelet to lymphocyte ratio on admission; PreRDW, red blood cell distribution width on admission; CRP, C-reactive protein; NSE, neuron-specific enolase; IL-6, interleukin-6.