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. Author manuscript; available in PMC: 2021 Mar 9.
Published in final edited form as: Am J Clin Nutr. 2019 Jul 1;110(1):158–168. doi: 10.1093/ajcn/nqz045

Table 2.

Sample sizes and percentages for serum vitamin B-12 and methylmalonic acid by variable categories in US persons ≥20 y of age, NHANES 2011–20141

Serum vitamin B-12 Serum MMA
Variable categories 2011–2012 2013–20142 2011–2012 2013–20142
n % n % n % n %
All 4,804 - 5,216 - 4,807 - 5,213 -
 Age, y
  20–39 1,670 35.2 1,705 35.2 1,670 35.1 1,703 35.2
  40–59 1,608 38.8 1,823 37.4 1,608 38.8 1,821 37.4
  60–69 800 14.0 866 14.8 800 14.0 867 14.8
  ≥70 726 12.0 822 12.6 729 12.1 822 12.6
 Sex
  Male 2,424 49.1 2,535 49.3 2,424 49.1 2,534 49.3
  Female 2,380 50.9 2,681 50.7 2,383 50.9 2,679 50.7
 Race-ethnicity
  Hispanic 974 14.3 1,172 14.7 974 14.3 1,174 14.8
   Mexican American 481 7.8 709 9.2 481 7.8 711 9.2
  Non-Hispanic Black 1,220 10.8 1,026 10.8 1,220 10.8 1,024 10.8
  Non-Hispanic White 1,805 67.4 2,279 66.6 1,807 67.4 2,275 66.6
  Non-Hispanic Asian 670 5.0 588 5.2 671 5.0 589 5.3
 B-12 supplement use
  No 3,303 66.1 3,514 64.1 3,304 66.0 3,515 64.1
  Yes 1,467 33.9 1,672 35.9 1,469 34.0 1,668 35.9
 Fasting
  <3 h 1,347 29.4 1,689 35.5 1,347 29.4 1,688 35.5
  3–<8 h 982 18.7 983 16.8 983 18.7 980 16.8
  ≥8 h 2,475 51.9 2,544 47.7 2,477 51.9 2,545 47.7
 Renal function
  Normal 3,730 82.2 3,989 80.1 3,731 82.2 3,987 80.1
  CKD stage 1–2 613 10.6 693 11.8 614 10.6 693 11.8
  CKD stage 3–5 424 7.3 482 8.1 425 7.3 481 8.1
1

Values are weighted percentages. Pregnant and lactating women were excluded; available-case analysis was used to handle missing or incomplete data (e.g., B-12 supplement use, renal function). CKD, chronic kidney disease; MMA, methylmalonic acid.

2

While NHANES 2013–2014 collected samples from participants ≥19 y of age, we only included data for participants ≥20 y of age.