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. 2018 Oct 7;2(2):e1139. doi: 10.1002/cnr2.1139

Figure 3.

Figure 3

Metabolic alterations observed in CD‐34+ CML cells: Increased fatty acid oxidation leads to elevated levels of acylcarnitines and increased enrichment of TCA cycle metabolites and amino acids from stable isotope labeled palmitate. TCA flux is also increased via the enhanced activity of anaplerotic enzyme pyruvate carboxylase