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[Preprint]. 2021 Mar 1:2021.02.27.433180. [Version 1] doi: 10.1101/2021.02.27.433180

Figure 2. T cell responses of COVID-19 convalescent individuals against SARS-CoV-2 proteome for the different variants.

Figure 2.

PBMCs of the COVID-19 convalescent individuals (n=11) were stimulated with the MPs for the entire viral proteome corresponding to the ancestral reference strain (Wu, black) and the B.1.1.7 (UK, grey), B.1.351 (SA, red), P.1. (BR, orange) and CAL.20C (CA, light blue) SARS-CoV-2 variants. A) Percentages of AIM+ (OX40+CD137+) CD4+ T cells for the total reactivity. B) Percentages of AIM+ (CD69+CD137+) CD8+ T cells for the total reactivity. Bars represent the geometric mean. Paired comparisons of Wuhan versus each of the variants were performed by Wilcoxon tests. C) Percentages of AIM+ (OX40+CD137+) CD4+ T cells for each MP D) Percentages of AIM+ (OX40+CD137+) CD4+ T cells for each MP.