Table 1.
Parameter | Definition | Value | Calculation | Reference | |
Basic reproduction number | 3.1 (1.9–6.5) | 41 | |||
Symptomatic rate | 0.792 (0.568–0.815) | 42–44 | |||
Infection rate for symptomatic transmissions | 0.62 (0.38–1.3) | 45 | |||
Reduction of infection rate for asymptomatic transmission | 0.55 (0.46–0.62) | 46 | |||
Infection rate for asymptomatic transmissions | 0.341 (0.175–0.806) | ||||
Clearance rate for asymptomatic/mild cases | 0.170 (0.0526–0.287) | 42 46 | |||
Clearance rate for symptomatic non-severe cases | 0.238 (0.143–0.333) | 47–49 | |||
Clearance rate for symptomatic severe cases | 0.238 (0.143–0.333) | 47–49 | |||
Incubation rate | 0.202 (0.101–0.364) | 50 51 | |||
Severe case fatality rate | 0.244 (0.209–0.280) | 17 52 | |||
Increase in rate of progression to severe disease in populations with TB or HIV/AIDS | 2.14 (1.1–2.7) | 16 17 | |||
Ages 0–64 | Ages 65–79 | Ages ≥80 | |||
Rate of progression to severe disease* | 0.202 (0.167–0.237) | 0.361 (0.286–0.435) | 0.471 (0.308–0.634) | 53 54 | |
Rate of progression to severe disease in populations with TB and/or HIV/AIDS | 0.432 (0.222–0.545) |
*Age groups are: 0–59, 60–69, 70+; 0–64, 65–74, 65+, US hospitalisation rate used as a proxy for severe disease progression.
TB, tuberculosis.