1. Estimated incidence of CRC in the world’s major burden countries and China in 2018.

Area	Population	Both				Male				Female
		New cases	Crude rate (1/105)	ASIRW (1/105)		New cases	Crude rate (1/105)	ASIRW (1/105)		New cases	Crude rate (1/105)	ASIRW (1/105)
CRC, colorectal cancer; ASIRW, age-standardized incidence rate by world standard population; a, Democratic Republic of Congo; b, Polynesia and Micronesia; c, Australia and New Zealand.
	World	1,849,518	24.2	19.7		1,026,215	26.6	23.6		823,303	21.8	16.3
	China	521,490	36.6	23.7		303,853	41.5	28.1		217,637	31.5	19.4
Asia
Eastern	Republic of Korea	42,363	82.8	44.5		26,143	102.1	59.5		16,220	63.4	31.3
South 　Eastern	Singapore	4,202	72.5	36.8		1,994	69.7	38.9		2,208	75.4	34.0
South 　Central	Kazakhstan	3,049	16.6	15.4		1,392	15.6	17.7		1,657	17.5	14.1
Western	Turkey	20,031	24.5	21.0		11,548	28.6	27.4		8,483	20.4	16.0
Europe
Western	Netherlands	14,921	87.3	37.8		8,513	100.1	45.3		6,408	74.7	31.1
Northern	Norway	4,887	91.3	42.9		2,530	93.6	46.9		2,357	88.9	39.3
Eastern	Hungary	10,809	111.6	51.2		6,115	132.6	70.6		4,694	92.4	36.8
Southern	Slovenia	1,987	95.5	41.1		1,301	125.8	58.9		686	65.5	25.5
Americas
Northern	Canada	24,617	66.6	31.5		13,039	71.1	35.2		11,578	62.2	28.0
Central	Costa Rica	1,128	22.8	16.7		560	22.6	17.6		568	22.9	15.9
Caribbean	Barbados	219	76.5	38.9		118	86.1	50.3		101	67.6	28.8
South	Uruguay	2,273	65.5	35.0		1,152	68.7	43.8		1,121	62.5	28.3
Africa
Northern	Algeria	5,537	13.2	13.9		2,910	13.7	14.8		2,627	12.6	13.0
Eastern	Mauritius	288	22.7	14.7		156	24.9	17.4		132	20.6	12.6
Southern	South Africa	6,937	12.1	14.4		3,508	12.5	18.1		3,429	11.7	12.0
Middle	Congoa	3,568	4.2	9.1		1,627	3.9	9.0		1,941	4.6	9.2
Western	Mali	917	4.8	10.5		385	4.0	9.0		532	5.6	11.7
Oceania
Melanesia	Papua New Guinea	684	8.1	13.0		439	10.3	19.3		245	5.9	8.4
Polynesiab	Samoa	37	18.7	22.6		24	23.5	30.6		13	13.6	14.8
Australiac	Australia	17,782	71.8	36.9		9,643	78.1	41.9		8,139	65.5	32.4