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. 2021 Mar 9;22:114. doi: 10.1186/s12859-021-04057-z

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© The Author(s) 2021

Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated in a credit line to the data.

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Fig. 1 — Workflow and main functions of Y-LineageTracker. The Y-LineageTracker supports taking VCF or BAM files as input data to perform NRY haplogroup classification and Y-STR genotyping. The outputs of haplogroup classification can be used as input data for subsequent clustering and phylogeny analysis, and the outputs of phylogeny analysis can be further used for time estimation. Similarly, the outputs of Y-STR genotyping can be used for statistical analysis and network analysis, and the output of network analysis can be further used for TMRCA estimation