Table 1.
Demographic and Clinical Characteristics
| Characteristic | N=567 |
|---|---|
| Age, years | 61 (51 to 70) |
| Female sex, n (%) | 232 (41%) |
| CFS Score at baseline, n (%) | |
| 1-Very Fit | 21 (4%) |
| 2-Well | 93 (16%) |
| 3-Well with treated comorbid disease | 193 (34%) |
| 4-Apparently vulnerable | 125 (22%) |
| 5-Mildly frail | 70 (12%) |
| 6-Moderately frail | 53 (9%) |
| 7-Severely frail | 12 (2%) |
| Charleson Comorbidity Index score | 2 (1 to 4) |
| Katz ADL score at baseline | 0 (0 to 1) |
| FAQ score at baseline | 0 (0 to 2) |
| IQCODE score | 3.0 (3.0 to 3.1) |
| APACHE II score at ICU admission | 23 (17 to 29) |
| Mean daily SOFA score in the ICU | 7 (5 to 9) |
| Deliriousc, n (%) | 397 (70%) |
| Duration of deliriuma, days | 3 (2 to 7) |
| Comatosed, n (%) | 294 (52%) |
| Duration of comaa, days | 2 (1 to 5) |
| Septicb, n (%) | 365 (65%) |
| Duration of sepsisa, days | 4 (2 to 8) |
| Mechanically ventilated, n (%) | 499 (88%) |
| Duration of mechanical ventilationa, days | 2 (1 to 6) |
| ICU length of stay, days | 5 (3 to 10) |
| Hospital length of stay, days | 10 (6 to 18) |
Data are median (interquartile range) unless otherwise indicated.
CFS= clinical frailty scale; ADL= activities of daily living; FAQ= functional activities questionnaire of instrumental ADLs; IQCODE= informant questionnaire on cognitive decline in the elderly; APACHE II= acute physiologic and chronic health evaluation, version II; SOFA= sequential organ failure assessment
a
Among those with the clinical condition
b
Defined according to Sepsis-2 definition for severe sepsis
c
Defined as the number of days the Confusion Assessment Method for the ICU was positive
d
Defined at the number of days the Richmond Agitation-Sedation Scale was −4 or −5.