Table 1.
Demographics of the cohort (P are calculated based on logistic regression analysis and Chi-square analysis)
| Control n=23 | Early AMD n=28 | CNVM n=21 | GA n=12 | AMD n=61 | |
|---|---|---|---|---|---|
| Sex (Female) | 47.60% | 50% | 28.60% | 8.30% | 30% |
| Age | 57±6 | 63±8 | 67±9 | 70±10 | 66±8 |
| Alcohol | Nil | 17.80% | 23.80% | 33.30% | 23% |
| Smoking | Nil | 10.70% | 23.80% | 16.70% | 16.40% |
| Tobacco | Nil | 14.30% | 28.60% | 8.30% | 18% |
| Diabetes | 14.30% | 28.60% | 28.60% | 33.30% | 29.50% |
| Hypertension | 28.60% | 42.90% | 38.10% | 41.70% | 41% |
| eGFR | 128±25 | 87.72±5 | 91.04±6.5 | 89.22±13.03 | 89.72±38.27 |
| CFHrs1061170(C*) | |||||
| CC | Nil | 4% | 4.80% | 8.30% | 3.50% |
| CT | 56.30% | 76% | 76.20% | 83.30% | 78.90% |
| TT | 43.80% | 20% | 19.00% | 8.30% | 17.50% |
| χ2-P | 0.15 | 0.13 | 0.09 | 0.09 | |
| C3 rs2230199(G*) | |||||
| GG | Nil | Nil | Nil | 8.30% | 0.80% |
| GC | 12.50% | 32% | 30% | 1.70% | 47.40% |
| CC | 87.50% | 68% | 70% | 50% | 50.90% |
| χ2-P | 0.188124 | 0.40421 | 0.00846 | 0.0949 |