Table 4.
Validation of differentially expressed proteins in AMD patients using ELISA
| Control | SERPINA-1 (n=23) | APOA-1 (n=22) | TIMP-1 (n=20) | |||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Median | 546 | 0.82 | 0.39 | |||||||||
| Mann whitney U test | EARLY AMD (n=25) | CNVM (n=23) | GA (n=12) | AMD (n=60) | EARLY AMD (n=24) | CNVM (n=20) | GA (n=12) | AMD (n=56) | EARLY AMD (n=26) | CNVM (n=23) | GA (n=12) | AMD (n=61) |
| Median | 1047 | 1143 | 430.6 | 1003 | 3.3 | 12.78 | 9.69 | 7.3 | 0.85 | 1.1 | 1.76 | 1.03 |
| Fold change | 2 | 2 | - | 2 | 4.02 | 15.59 | 11.81 | 8.9 | 2.18 | 2.82 | 4.51 | 2.64 |
| P | 0.044 | 0.027 | 0.87 | 0.049 | 0.1 | 0.003 | 0.008 | 0.003 | 0.12 | 0.01 | 0.02 | 0.01 |